Newsletter #17
October 1st, 2024

Dear all,

We hope you had a nice september! At BioConvS we've been busy preparing plenty of initiatives for the end of 2024, most importantly save the dates for these two back-to-back events:

📅Attend the BioConvS annual's symposium on November 28th > Innovation Day: Matchmaking

📅Attend the first SynBioTherapy conference on November 27th to discover the synthetic biology revolution in biotherapy

Innovation Day:
Matchmaking

👉find partners for collaborative projects
👉submit an abstract for a poster or a short talk
👉discover our platforms and funding opportunities
👉explore the ecosystem of BioConvS
👉meet Ile-de-France's tech transfer experts

DIM Events

BioConvS and the PEPR Biothérapies organise a bridging event between their two annual symposiums to discuss about synergies between biotherapies and synthetic biology and to design the biotherapies of the future.

Opportunities

Opening soon: BioConvS postdoc call
Our second postdoc call will open in october. Stay tuned for further info!

EIT Health Re-Industrialisation of Europe Flagship Call 2024

a grant of up to € 1million to up to 8 projects which will deliver innovative solutions that provide immediate, tangible benefits and foundational support to the IPCEI Med4Cure workstreams.
Project consortia should consist of one IPCEI Med4Cure direct partner or associated partner, one micro or small enterprise, and at least one academic organisation (research institute, university, hospital) or healthcare service provider.

Get free access to the ISCT Advanced Cell Therapy Manufacturing and Regulatory Course

A few individual yearly licenses are still available for of our Basic Lab Membership You can apply to access the ISCT network and training material, which notably includes the Advanced Cell Therapy Manufacturing and Regulatory Course, and much more!

Creative Destruction Lab
Bioconvergence stream

HEC and BioConvS are joining forces to launch CDL-BIOCONVERGENCE, an international-scale start-up accelerator in Île-de-France focused on health biotechnologies, to accelerate the transformation of scientific discoveries into innovations by leveraging the strengths of DIM BioConvS, reinforced by a proven international accelerator model, CDL.

MOOC Innover avec la recherche publique
The MOOC "Innovating with public research" produced by SATT Ouest Valorisation and the C.U.R.I.E Network is an online certification training course that covers all aspects of the valorization of research work. It is aimed at researchers and doctoral students as part of their awareness of the valorization of their research results. The new certification session starts on October 14!

October 10th
Accor Arena - Paris

Discover the winners of iPhD, iLab, iNov
iLab, iPhD, and iNov are French innovation support programs. iLab fosters early-stage startups, iPhD targets PhD students to turn research into business, and iNov funds high-potential innovative projects. Discover the list of the 2024 laureates!

Matinale « Les nouveaux acteurs des biothérapies »
You can attend a Deeptech morning session either in person or via video on the topic of new players in biotherapies on November 7th.

Census of BioConvS labs
Starting January 2024, all labs affiliated or wanting to participate in a DIM BioConvS activity will have to be registered. Why? Most importantly because we want to build a cartography of biotherapy, bioproduction and synthetic biology in Ile-de-France and you want to make sure that you're on it!

Recent publications

Do you want to see your paper featured in our next newlsetter? Write to chiara.fracassi@u-paris.fr

Alcantar, M.A., English, M.A., Valeri, J.A., Collins, J.J., 2024. A high-throughput synthetic biology approach for studying combinatorial chromatin-based transcriptional regulation. Molecular Cell 84, 2382-2396.e9. https://doi.org/10.1016/j.molcel.2024.05.025

Bredon, M., Danne, C., Pham, H.P., Ruffié, P., Bessede, A., Rolhion, N., Creusot, L., Brot, L., Alonso, I., Langella, P., Derosa, L., Cortot, A.B., Routy, B., Zitvogel, L., Segata, N., Sokol, H., 2024. Faecalibaterium prausnitzii strain EXL01 boosts efficacy of immune checkpoint inhibitors. OncoImmunology 13, 2374954. https://doi.org/10.1080/2162402X.2024.2374954

Caliendo, F., Vitu, E., Wang, J., Kuo, S.-H., Sandt, H., Enghuus, C.N., Tordoff, J., Estrada, N., Collins, J.J., Weiss, R., 2024. Customizable gene sensing and response without altering endogenous coding sequences. Nat Chem Biol 1–12. https://doi.org/10.1038/s41589-024-01733-y

Durrant, M.G., Perry, N.T., Pai, J.J., Jangid, A.R., Athukoralage, J.S., Hiraizumi, M., McSpedon, J.P., Pawluk, A., Nishimasu, H., Konermann, S., Hsu, P.D., 2024. Bridge RNAs direct programmable recombination of target and donor DNA. Nature 630, 984–993. https://doi.org/10.1038/s41586-024-07552-4

Hiraizumi, M., Perry, N.T., Durrant, M.G., Soma, T., Nagahata, N., Okazaki, S., Athukoralage, J.S., Isayama, Y., Pai, J.J., Pawluk, A., Konermann, S., Yamashita, K., Hsu, P.D., Nishimasu, H., 2024. Structural mechanism of bridge RNA-guided recombination. Nature 630, 994–1002. https://doi.org/10.1038/s41586-024-07570-2

Vendomèle, J., Chauveau, G.A., Dalkara, D., Galy, A., Fisson, S., 2024. Peripheral Cellular Immune Responses Induced by Subretinal Adeno-Associated Virus Gene Transfer Can Be Restrained by the Subretinal-Associated Immune Inhibition Mechanism. Human Gene Therapy. https://doi.org/10.1089/hum.2023.191

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